Cointreau is a brand of triple sec (an orange-flavoured liqueur) produced in Saint-Barthélemy-d'Anjou, France. It is drunk as an apéritif and digestif and is a component of several well-known cocktails. It was originally called "Curaçao Blanco Triple Sec". Cointreau Distillery was set up in 1849 by Adolphe Cointreau, a confectioner, and his brother Edouard-Jean Cointreau. Their first success was with the cherry liqueur guignolet, but in 1875 they found success when they blended sweet and bitter orange peels and pure alcohol from sugar beets. 43% Vol.